self tolerance meaning in English
自身耐受性
自体耐性
Examples
- Immunoregulation mediated by regulatory t cell is one of the most important mechanisms to maintain self tolerance
调节性t细胞介导的免疫调节是自身耐受的重要机制之一。 - Recently , accumulating evidences have shown that regulatory t cells play a key role both in maintenance of self tolerance and tolerance to allograft
近年来，调节性t细胞在自身耐受和抑制同种异体排斥反应中的作用受到越来越多的重视。 - Naa can not only defend the invasion of various microorganism , but maintain the stability of internal envioment , lead to self tolerance , regulate immunity and prevent tumor progression
从不同角度对naa的研究显示： naa的产生可能与自身反应性b细胞克隆阳性选择过程有关； naa对外可以抵御外来微生物的入侵；对内可以维持机体内环境的稳定，引起自身耐受，调节免疫和抗肿瘤。 - Thus , it will help elucidate the development , self tolerance of self autoreactive b lymphocyte repetoire to investigate the generation of naa . researches on the function of naa will help clarify the significance of naa ' s existence . the exploration of biological nature , encoded gene and the difference or relation between naa and pathological autoantibody will shed much light on the pathological mechanism and treament of autoimmune disease
因此，对naa产生机理的揭示将有助于回答免疫学b细胞产生、发育以及自身耐受的问题；对naa功能的研究有助于进一步明确naa对机体的意义；对naa的特性、编码基因、与病理性自身抗体界限和关系的研究可能对自身第四军医大学硕士学位论文免疫疾病的发病机制和治疗提供有益的线索。 - In terms of regulatory t cell , cd4 + cd25 + t cell is representitive . ln naive individuals , cd4 + cd25 + t cells function as self tolerance , in recipients with long term survival allograft . they play an important role in suppression of allograft rejection . immune regulation potent cd4 + cd25 + t cells can be recovered from recipients with long term survival allografts . such regulatory t cells can suppress t cell mediated rejection in vitro and in vivo
其中， cd4 + cd25 + t细胞是具有代表性的调节性t细胞。在未经处理的机体内， cd4 + cd25 + t细胞对保持自身耐受起着关键的作用。在同种异体移植物长期存活的受体内， cd4 + cd25 + t细胞对抑制同种异体移植物排斥反应也起到很重要的作用。